Hepatocellular Carcinoma

Creating a Multidisciplinary Hepatocellular Carcinoma Clinic Improves Survival

Forming a multidisciplinary clinic for patients with HCC resulted in improved survival, likely due to more streamlined care and earlier diagnosis, found research presented at SSO 2013.

Survival After Radiofrequency Ablation Might be 'Comparable' to Resection for Liver Cancer

Radiofrequency ablation might offer comparable survival rates when compared with liver surgery for patients with hepatocellular carcinoma.

Aspirin Use Associated with Lower Liver Cancer Risk and Chronic Liver Disease Mortality Rates

Aspirin use, but not the use of other nonsteroidal anti-inflammatory drugs (NSAIDs), is associated with a reduced risk of developing hepatocellular carcinoma.

RSNA: DEB TACE Viable Treatment Option for Advanced Unresectable HCC

Patients with advanced unresectable hepatocellular carcinoma have a higher median overall survival when treated with drug eluting bead transarterial chemoembolization.

DEBs and the Treatment of Unresectable HCC

Drug-eluting beads are a new type of drug delivery system that may be able to decrease side effects and localize chemotherapy treatment in HCC patients.

Clinical Trial for Novel Liver Cancer Drug Begins

The first patient has been treated in a phase 2 clinical trial of intravenous delivery JX-594 in patients with advanced hepatocellular carcinoma.

No Survival Gains with Erlotinib, Sorafenib in Liver Cancer

First-Line Brivanib Fails Against Sorafenib on OS End Point in HCC

In a randomized phase 3 trial, first-line brivanib did not meet its primary overall survival end point in patients with hapatocellular carcinoma.

Patients with Alcoholic Cirrhosis at Low Risk for HCC; Surveillance Not Warranted

A cohort study of Danish patients with alcoholic cirrhosis suggests that because they are at low risk for hepatocellular carcinoma (HCC), "surveillance would be expected to have a minimal effect on mortality and is unlikely to be cost effective,"

Tivantinib Improves Survival in HCC Patients

Family History of Liver Cancer, HBV/HCV Infection Increase Risk of HCC

The investigators sought to understand the relationships between familial clustering of hepatocellular carcinoma (HCC), family history of liver cancer and the incidence of hepatitis.

Childhood Obesity Increases Risk of Adult HCC

Danish researchers have established a link between childhood obesity and hepatocellular carcinoma (HCC) in adults.

SIRT-Sorafenib Combination Shows Efficacy in Patients with HCC

Loco-regional therapy with selective internal radiation therapy (SIRT) and sorafenib demonstrated good efficacy in patients with advanced hepatocellular carcinoma (HCC), especially those in Barcelona Clinic Liver Criteria (BCLC) stage B.

Antisense Drug Makes Sense as Potential Broad-Acting Cancer Therapy

The search for a drug that can treat many different forms of cancer may be over. This comes with news that Isis Pharmaceuticals has initiated a Phase 1 study targeting the expression in tumors of signal transducer and activator of transcription 3 (STAT3), a gene that is ubiquitous and overexpressed in many tumor types.

TACE + Sorafenib Delays HCC Progression in Patients with Chronic HCV Infection

Transarterial chemoembolization (TACE) with sequential sorafenib delayed time to progression (TTP) of intermediate-stage hepatocellular carcinoma (HCC) in patients with chronic hepatitis C virus (HCV) infection, a prospective randomized study concluded in The Oncologist online February 14.